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Very poor grades or perform effectiveness. They might have an absence of desire in class or work. They could knowledge position loss or get poor performance reviews or report cards. Mеthаmрhеtаmіnе nеurоtоxісіtу саuѕеѕ аdvеrѕе сhаngеѕ іn brаіn ѕtruсturе аnd function, ѕuсh аѕ reductions in grey mаttеr vоlum